A case series of 39 U.S. veterans with mild traumatic brain injury (mTBI) showed a 46.6% average symptom improvement after 40 sessions of HBOT at 1.5 ATA. Brain perfusion improved significantly on SPECT scans, with common benefits including better sleep, mood, and reduced pain—highlighting HBOT as a promising therapy for long-term neurological recovery.
A recent case series examined the use of hyperbaric oxygen therapy (HBOT) in 39 U.S. veterans suffering from persistent symptoms of mild traumatic brain injury (mTBI). After completing 40 HBOT sessions at 1.5 ATA, participants showed significant improvements in both brain perfusion (measured by SPECT imaging) and overall symptom reduction—including improved sleep, mood, and pain levels. On average, veterans reported a 46.6% improvement in symptoms.
Study Overview
Title: A Case Series of 39 United States Veterans with Mild Traumatic Brain Injury Treated with Hyperbaric Oxygen Therapy
Quick Summary: This case series followed 39 U.S. veterans with chronic mTBI who completed a short-term HBOT program. Before and after brain scans showed better blood flow to the brain, and most participants reported improved symptoms, including reduced pain and better sleep.
Key Findings:
Brain perfusion improved significantly on SPECT scans (p < 0.001)
Participants reported an average 46.6% improvement in symptoms
Common improvements included better sleep, mood, and less pain
Study Details:
Sample Size: 39 veterans (36 men, 3 women; ages 28–69)
Treatment Protocol:
40 HBOT sessions
90 minutes per session at 1.5 ATA, 100% oxygen
Delivered twice daily over 20 weekdays
Outcome Measures:
SPECT brain imaging (pre- and post-treatment)
Multi-symptom self-reports
Year Published: 2022
Where Published: Medicines (MDPI)
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Read Full Study on MDPI
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